So, Python isn't really a CMS topic unless you're a Plone user. However, as my world at work slowly moves from Python to Java as the language of choice...I'll promote this underdog open source language anytime. From the IBM developerWorks site:
Adopt Python to manage UNIX® systems while incorporating concepts of good program design. Python is an easy-to-learn, open source scripting language that lets system administrators do their job more quickly. It can also make tasks more fun.